Understanding vpxuser Permissions

The vpxuser permission is used for vCenter Server when managing activities for the host. The vpxuser is created when an ESXi host is attached to vCenter Server.

vCenter Server has Administrator privileges on the host that it manages. For example, vCenter Server can move virtual machines to and from hosts and perform configuration changes needed to support virtual machines.

The vCenter Server administrator can perform most of the same tasks on the host as the root user and also schedule tasks, work with templates, and so forth. However, the vCenter Server administrator cannot directly create, delete, or edit users and groups for ESXi hosts. These tasks can only be performed by a user with Administrator permissions directly on each ESXi host.

Note

You cannot manage the vpxuser using Active Directory.

 Caution

Do not change vpxuser in any way and do not change its permissions. If you do so, you might experience problems in working with ESXi hosts through vCenter Server.

Source:-

Vmware Documentation